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How will we know if the project has been successful?

posted Jul 15, 2012, 5:33 PM by Anitha Kannan   [ updated Jul 15, 2012, 5:36 PM ]

Despite multiple large international biological databases housing genomic and protein data, there is currently no single system that integrates up-to-date pertinent information from each of these data repositories and assembles the information into a format suitable for a global proteomics effort of the type proposed by the Chromosome-centric Human Proteome Project (C-HPP).

This project aims to produce a data integration and analysis software system for the C-HPP effort and to make data collections from this resource discoverable through ANDS's Research Data Australia. The Proteome Browser will assist Australian and international efforts in completing a map of the Human Proteome. The mapping of the human proteome, even a partial mapping, will help elucidate biological and molecular function and provide advance diagnosis and treatment of diseases. It’s approach may also be applied to other animals and plants.

This software needs to be:

  • Easy to use
  • A visualisation tool designed to display an overview of the current evidence supporting the identification of various gene products across the chromosome, such as protein expression, modification and disease association, with the ability to drill down to the original data
  • Extensible, to allow for easy addition of both new data sources and data categories

To achieve these objectives we will:

  • Design the software to be ultimately species and chromosome independent, whilst maintaining the initial focus on the development of a resource for Human Chromosome 7
  • Have two Product Owners involved in this project, one representing Proteomic researchers and the other ANDS. The Product Owners will contribute towards the features to be developed and set priorities on when these features are developed. They will also seek guidance from the project’s steering committee.
  • Have a steering group /advisory committee for the project which will comprise of key members from the Australian and international Proteomics community.
  • Ensure that the application is built to a high quality and meets the needs of the researchers via a test strategy that includes unit testing, system testing and integration testing by the development team; followed by user acceptance test by members of the Proteomics research community.
    When the Product Owners select a version for release to the Production Environment, a selection of stakeholders across the Australian C-HPP effort will test the version in the Staging Environment as a part of the user acceptance test of the release to determine if the user requirements have been met.

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